UBEGlobalEyeAutumn1995Number3October1,1995pagePublishedbythePublicRelationsGrp.ofUBEIndustries,Ltd.Inaddition,in1990welaunchedCVMEandCytosine,whichareproducedfromDMPN,andwearelookingformarketopportunitiesforvariousheterocyclessuchasaminopyrazols,aminoisoxazolsandaminopyrimidines.DevelopmentofDMCIn1993,a3,000-tondimethylcarboxylate(DMC)plantwascompletedandmarketdevelopmentisunderwayforthismaterialaswellasforitsderivatives.Onederivative,polycarbonatediol,hasbeenreleasedforsale.•DMAD(1,3-Dimethylacetonedicarboxylate)Application:pharmaceuticalintermediate•DMO(Dimethyloxalate)Application:cosmeticfragrances•DMPN(3,3-Dimethoxypropionitrile)Application:pharmaceuticalintermedi-ate(vitaminB1intermediate)•CVME(3-Methoxyacryronitrile)Application:pharmaceuticalintermediates•CytosineApplication:pharmaceuticalintermedi-ates•DMPM(Methyl3,3-dimethoxypropionitrite)Application:pharmaceuticalintermedi-atesTheFiveTreesofUBE'sFineChemicalsUBE’smorethan80finechemicalproductsareusedinavarietyoffieldssuchaschemicals,pharmaceuticals,agriculture,fragrances,food,andadhesives.Althoughfinechemicalsarecutting-edgeproducts,theirrootsliedeepinourcompanyhistory,beingthecornerstoneofthechemicalbusiness.Tounderstandourfinechemicalproducts,wehavegroupedthemaccordingtobasictechnologiesaswellassourcematerialsandrepresentedthemasthefive“finechemicaltrees.”Theactualdevelopmentofproductsis,ofcourse,muchmorecomplicatedthanthesetrees,havingmorebranchesandleavesandmoreintertwiningbranches.Wehaverepresentedtheproductsinfivetreestosimplifytheirhistory.SpecialFeatureMolecularstructureofpyrimidifen—activeingredientofMiteclean(Source:AgrochemicalResearchGroup,UbeLaboratory)theseflavorsandfragrancessince1975.Theseflavorsandfragrancesaresoldprimarilyoverseas.UBEistheworld’slargestmanufacturerofGL-900andGL-1100,andshipsthemajorityoftheworldsupply.•g-Nonalactone<GL-900>Coconutflavor•g-Untecaralactone<GL-1100>Peachflavor•(Cycloten)Caramelflavor3.NitriteTechnologyTreeNitrite(R-ONO)isthenamefornitrousester,andisproducedfromalcoholandNOx.NitritetechnologyisUBE’suniqueoxidationprocessonwhichpalladiumiscombinedwithnitritetoproducevariousfinechemicals.Thehistoryofthistechnologyandresultingproductsaredescribedbelow.OxalicAcidProductionbyaNewProcessUBEdevelopedarevolutionarycatalystsystemcombiningpalladiumandalkylnitrite.Thisnewcleansystemwasappliedtoourbusinessin1978byproducingdibutyloxalatefromcarbonmonoxideandbutanolbytheCO-couplingmethodandusinghydrolysistoconvertthistooxalicacid.Thiscatalystsystemofpalladiumandnitritewassubsequentlydevelopedforapplicationsinotheroxy-carbonylationreactions.Wefoundthatthiscanbeappliedtodicarboxylatesuchasdimethylmalonateanddimethylsuccinate,anddevelopedtherespectivetechnologiestohighlevels.DevelopmentofOxi-acetalizationReactionsWehavealsopursuedresearchtoapplyoxidationreactionsotherthanoxi-carbonylation,whichresultedinourdiscoveryoftheoxi-acetalizationreactionolefins.Inthisreaction,DMPNisproducedfromacrylonitrileandundergoesseveralstepstobecomediamine—avitaminB1intermediate.1.Pharma&AgrochemicalsTreeCurrentproductscanbedividedintoagrochemicals,whichUBEdevelopedindependently,andpharmaceuticalchemicals,whichUBEproducesundercontractfrompharmaceuticalmanufacturers.ProductsDevelopedbyUBE:•Pefrazoate—anactiveingredientofHealthied,aseedfungicideforrice•Pyrimidifen—anactiveingredient...
